Utility of Laboratory Test Result Monitoring in Patients Taking Oral Terbinafine or Griseofulvin for Dermatophyte Infections
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چکیده
منابع مشابه
Activity of terbinafine in experimental fungal infections of laboratory animals.
The allylamine derivative terbinafine is the first antifungal agent with primary fungicidal properties against dermatophytes which acts systemically after oral application as well as locally after topical application. Comparative oral studies carried out with griseofulvin and ketoconazole in model infections such as guinea pig trichophytosis and microsporosis revealed terbinafine to be superior...
متن کاملAnti Dermatophyte Activities of Eucalyptus camaldulensis in Comparison with Griseofulvin
Methanolic leaf extracts of Eucalyptus camaldulensis were investigated for in vitro antifungal activities against Microsporum canis, Microsporum gypseum, Tricophyton rubrum, Tricophyton schoenleinii, Tricophyton mentagrophytes and Epedermophyton floccosum. The studies were carried out using broth dilution method, agar dilution method and inhibitory zone estimation. The effects of the plant extr...
متن کاملDermatophyte test medium culture for evaluating toenail infections in patients with diabetes.
OBJECTIVE To evaluate the performance of the in-office dermatophyte test medium (DTM) culture when used to confirm the diagnosis of onychomycosis in diabetic patients. RESEARCH DESIGN AND METHODS Nail samples from 184 diabetic patients who exhibited symptoms consistent with toenail onychomycosis were screened for dermatophyte fungal infection using DTM, potassium hydroxide evaluation, and cen...
متن کاملUptake of Griseofulvin by the Sensitive Dermatophyte, Microsporum Gypseum.
El-Nakeeb, Moustafa A. (Rutgers, The State University, New Brunswick, N.J.), and J. O. Lampen. Uptake of griseofulvin by the sensitive dermatophyte, Microsporum gypseum. J. Bacteriol. 89:564-569. 1965.-Actively growing cultures of Microsporum gypseum took up large amounts of griseofulvin-(4-methoxy-H(3)) from the medium. Initially, most of the material could be extracted with hot water, but the...
متن کاملShort term treatment of dermatophyte onychomycosis with terbinafine.
OBJECTIVE To evaluate the effect of short term treatment with terbinafine on dermatophytosis. DESIGN Multicentre, randomised, double blind placebo controlled trial of 250 mg/day terbinafine for 12 weeks in dermatophyte onychomycosis. SETTING Eight dermatology centres in the United Kingdom. PATIENTS 112 patients (mean age 44, range 19-78), 99 with mycologically proved toenail infections an...
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ژورنال
عنوان ژورنال: JAMA Dermatology
سال: 2018
ISSN: 2168-6068
DOI: 10.1001/jamadermatol.2018.3578